Rare Pediatrics News

Disease Profile

Listeria infection

Prevalence
Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.

Unknown

Age of onset

All ages

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ICD-10

A32.0 A32.1 A32.7 A32.8 A32.9

Inheritance

Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease

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Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype

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X-linked
dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.

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X-linked
recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder

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Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.

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Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.

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Not applicable

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Other names (AKA)

Listeriosis; Listeria monocytogenes infection

Categories

Bacterial infections

Summary

A listeria infection or listeriosis is an infection caused by a bacteria known as Listeria monocytogenes. It mainly affects newborn infants, elderly patients, pregnant women and patients who have low immunity.[1] Listeria can be spread by several methods. A common cause is ingestion (food-borne transmission) of unpasteurized milk or contaminated vegetables. It can also be transmitted from mother to fetus during pregnancy or directly to the newborn at the time of delivery.[2] Listeriosis can cause a variety of symptoms, depending on the person and the part of the body affected. Pregnant women typically have only fever and other flu-like symptoms, such as fatigue and muscle aches. However, infections during pregnancy can lead to miscarriage, stillbirth, premature delivery, or life-threatening infection of the newborn, including generalized infection (sepsis) or inflammation of the membranes that cover the brain (meningitis). Sometimes listeriosis involves many organs and presents with masses filled with pus (microabscesses or granulomas). Older children with Listeria infections frequently develop meningitis.[1][3][2] Treatment include antibiotics such as ampicillin and aminoglycosides.[1]

Symptoms

This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.

Medical Terms Other Names
Learn More:
HPO ID
80%-99% of people have these symptoms
Fever
0001945
30%-79% of people have these symptoms
Bacteremia
0031864
Chills
0025143
Fatigue
Tired
Tiredness

[ more ]

0012378
Headache
Headaches
0002315
Hypoglycorrhachia
Low glucose levels in cerebral spinal fluid
0011972
Increased CSF protein
0002922
Meningitis
0001287
Myalgia
Muscle ache
Muscle pain

[ more ]

0003326
Nausea
0002018
Stiff neck
Neck stiffness
0025258
Vomiting
Throwing up
0002013
5%-29% of people have these symptoms
Abdominal pain
Pain in stomach
Stomach pain

[ more ]

0002027
Abnormality of the anterior fontanelle
Abnormality of the forehead soft spot
0000236
Arthralgia
Joint pain
0002829
Ataxia
0001251
Back pain
0003418
Brain abscess
0030049
Cranial nerve paralysis
0006824
Diarrhea
Watery stool
0002014
Hemiparesis
Weakness of one side of body
0001269
Immunodeficiency
Decreased immune function
0002721
Irritability
Irritable
0000737
Loss of consciousness
Passing out
0007185
Myoclonus
0001336
Nuchal rigidity
0031179
Premature birth
Premature delivery of affected infants
Preterm delivery

[ more ]

0001622
Pyelonephritis
0012330
Respiratory failure
0002878
Seizure
0001250
Sensory impairment
0003474
Spontaneous abortion
0005268
Tremor
0001337
1%-4% of people have these symptoms
Abnormal brainstem MRI signal intensity
0012747
Acute kidney injury
0001919
Arteritis
Inflammation of artery
0012089
Cholecystitis
Gallbladder inflammation
0001082
Congestive heart failure
Cardiac failure
Cardiac failures
Heart failure

[ more ]

0001635
Conjunctivitis
Pink eye
0000509
Disseminated intravascular coagulation
0005521
Encephalitis
Brain inflammation
0002383
Endocarditis
0100584
Functional motor deficit
0004302
Hearing impairment
Deafness
Hearing defect

[ more ]

0000365
Hepatic granulomatosis
0011955
Intellectual disability
Mental deficiency
Mental retardation
Mental retardation, nonspecific
Mental-retardation

[ more ]

0001249
Intermittent generalized erythematous papular rash
0007432
Jaundice
Yellow skin
Yellowing of the skin

[ more ]

0000952
Liver abscess
0100523
Myocarditis
Inflammation of heart muscle
0012819
Osteomyelitis
Bone infection
0002754
Pericarditis
Swelling or irritation of membrane around heart
0001701
Peritonitis
0002586
Pneumonia
0002090
Pustule
Pimple
0200039
Respiratory distress
Breathing difficulties
Difficulty breathing

[ more ]

0002098
Rhabdomyolysis
Breakdown of skeletal muscle
0003201
Sepsis
Infection in blood stream
0100806
Septic arthritis
0003095
Splenic abscess
0025059
Stroke
0001297
Unusual skin infection
0032162
Visual loss
Loss of vision
Vision loss

[ more ]

0000572

Learn more

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

Where to Start

  • You can obtain information on this topic from the Centers for Disease Control and Prevention (CDC). The CDC is recognized as the lead federal agency for developing and applying disease prevention and control, environmental health, and health promotion and education activities designed to improve the health of the people of the United States.
  • Mayo Clinic has an information page on Listeria infection.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.

In-Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.

References

  1. Zach T. Listeria Infection. Medscape Reference. October 20, 2015; https://emedicine.medscape.com/article/965841-overview.
  2. Listeriosis. Department of Health NY State. 2011; https://www.health.ny.gov/diseases/communicable/listeriosis/fact_sheet.htm.
  3. Listeria. Centers for Disease Control and Prevention (CDC). 2017; https://www.cdc.gov/listeria/symptoms.html.